The short answer, analysts say, is no.
South Korea’s multi-layered air defense network, known as the Korea Air and Missile Defense, cannot fully protect the country from a large-scale missile or artillery barrage by North Korea. The system is designed to limit damage, not to guarantee safety.
Overall, an expert judged that if North Korea were to launch multiple types of weapons simultaneously, it would be difficult to block them all with this network alone.
“Even with a multi-layered defense in place, many experts, including myself, believe that the system on its own would struggle to withstand a mixed, simultaneous strike from North Korea,” said Hong Min, a senior researcher at the Korea Institute for National Unification.
Experts also note that the proximity between the two Koreas, with Seoul 40 kilometers away from the Demilitarized Zone, leaves the South with very little reaction time if the North decides to strike. Long-range artillery could strike the capital in minutes, they say.
Korea Herald
You can read more at the link, but the difference between Israel and North Korea is the long range artillery. Israel largely eliminated Hezbollah prior to the confrontation with Iran in order to limit the rocket attacks from Lebanon. During a conflict with North Korea, Seoul could be pummeled with artillery fire which would require an extensive number of C-RAM batteries to intercept which the ROK or the USFK does not have.
Another difference in a battle with North Korea is the volume of missiles fired. Iran due to its distance from Israel had limited number of launchers to fire longer range missiles. Due to how close South Korea is, North Korea can use short and medium range ballistic missile launchers to target South Korea. Both the ROK and USFK have missile defense units to defend against these threats, but the question becomes how many interceptors do they have compared to North Korea’s ballistic missile inventory?